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The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma.

Fujita Y, Shibata A, Ogimoto I, Kurozawa Y, Nose T, Yoshimura T, Suzuki H, Iwai N, Sakata R, Ichikawa S, Tamakoshi A

Department of Public Health, Kurume University School of Medicine, Kurume 830-0011, Japan. yf123@med.kurume-u.ac.jp

We evaluated the interaction between hepatitis C virus (HCV) and cigarette smoking on death from hepatocellular cancer in The Japan Collaborative Cohort Study. The odds ratio of death from HCC for smoking was 9.60 (1.50-61.35) and 1.71(0.58-5.08) among anti-HCV positive and negative individuals, respectively.

Published 8 March 2006 in Br J Cancer, 94(5): 737-9.
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